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Scientists doubt that COVID can directly strike the cells of vessels

European and Chinese scientists have come to the conclusion that coronavirus extremely rarely can directly penetrate the cells of blood vessels, since they almost do not work out the molecules of the ACE2 protein, which are the main “conductor” of the SARS-COV-2 virus, according to a publication in the electronic BiorXIV library.
'Thrombs and problems with the functioning of vessels were one of the most striking features of Covid-19, which compelled scientists to consider that the virus was capable of directly striking their cells. But according to the data obtained by us, it turned out that SARS-COV-2 is hardly capable of directly penetrating into them and spreading into the endothelial tissue of the vessels. The virus rather strikes neighboring epithelial cells or damages vessels indirectly,” the researchers found, transmits BTA.

The International Scientific Collective under the direction of Prof. Andrew Baker, from Edinburgh University in the UK, doubted the pathogen's ability to directly disrupt the work of arteries, veins and capillaries, infecting their cells.

Analyzing the activity of all genes at level

individual cells in the human body, scientists came to the conclusion that all types of endothelial tissue from which the blood vessels are composed do not actually produce ACE2 in the body of healthy people.

The same situation is observed with the development of inflammation, typical for cases of severe coronavirus infection.

From the observations made, the team came to the conclusion that coronavirus can strike the cells of the walls of blood vessels in other ways using other receptors. Its most likely spread is by disrupting the work of immune cells and platelets. Another way is by infecting the epithelial cells present inside the vessels or adjacent to them.

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